[Hair follicle regeneration].
Study Design
- Loại nghiên cứu
- Review
- Đối tượng nghiên cứu
- None
- Thời gian
- 520 weeks
- Can thiệp
- [Hair follicle regeneration]. None
- Đối chứng
- None
- Kết quả chính
- [Hair follicle regeneration].
- Xu hướng hiệu quả
- Mixed
- Nguy cơ sai lệch
- Unclear
Abstract
Hair growth cycle is coordinated with complex processes that are dependent on the interactions of follicular stem cells and dermal papilla cells (DPCs). For the past 10 years, the developmental mechanism of hair follicles has been extensively studied, and spatial and temporal expressions of many molecules are required for the hair morphogenesis. These molecules are also required for hair cycle progression. Androgen receptor, which is a ligand dependent transcription factor, plays an important role in human hair cycle. Frontal scalp DPCs from androgenetic alopecia (AGA) are the target cells of androgen action. Minoxidil and Finasteride were recently introduced for the treatment of AGA, and cell therapy using DPCs is a next strategy for the innovative treatment.
Tóm lược
Frontal scalp DPCs from androgenetic alopecia (AGA) are the target cells of androgen action, and cell therapy using D PCs is a next strategy for the innovative treatment.
Used In Evidence Reviews
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