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HairCited

[Hair follicle regeneration].

Satoshi Itami
Review Nihon rinsho. Japanese journal of clinical medicine 2008 6 trích dẫn
PubMed
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Study Design

Loại nghiên cứu
Review
Đối tượng nghiên cứu
None
Thời gian
520 weeks
Can thiệp
[Hair follicle regeneration]. None
Đối chứng
None
Kết quả chính
[Hair follicle regeneration].
Xu hướng hiệu quả
Mixed
Nguy cơ sai lệch
Unclear

Abstract

Hair growth cycle is coordinated with complex processes that are dependent on the interactions of follicular stem cells and dermal papilla cells (DPCs). For the past 10 years, the developmental mechanism of hair follicles has been extensively studied, and spatial and temporal expressions of many molecules are required for the hair morphogenesis. These molecules are also required for hair cycle progression. Androgen receptor, which is a ligand dependent transcription factor, plays an important role in human hair cycle. Frontal scalp DPCs from androgenetic alopecia (AGA) are the target cells of androgen action. Minoxidil and Finasteride were recently introduced for the treatment of AGA, and cell therapy using DPCs is a next strategy for the innovative treatment.

Tóm lược

Frontal scalp DPCs from androgenetic alopecia (AGA) are the target cells of androgen action, and cell therapy using D PCs is a next strategy for the innovative treatment.

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