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Congenital alopecia areata.

Patsy Lenane, Elena Pope, Bernice Krafchik
Case Report Journal of the American Academy of Dermatology 2005 44 trích dẫn
PubMed DOI
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Study Design

Loại nghiên cứu
Case Reports
Cỡ mẫu
4
Đối tượng nghiên cứu
Neonates/infants with congenital alopecia areata
Thời gian
156 weeks
Can thiệp
Congenital alopecia areata. Clobetasol propionate 0.05%, minoxidil 2%
Đối chứng
None
Kết quả chính
Hair regrowth
Xu hướng hiệu quả
Positive
Nguy cơ sai lệch
High

Abstract

Alopecia areata, the alleged autoimmune process leading to nonscarring hair loss, is not uncommon. It has been classified as an acquired cause of alopecia; however, recently it has been reported in the neonatal period. We report 4 cases of congenital alopecia areata with follow-up from 3 to 5 years. The diagnosis was made clinically in all cases. All patients had prolonged periods of quiescence of hair loss ranging from 6 to 24 months. Treatments used included minoxidil 2% and a range of topical steroids including hydrocortisone 1%, betamethasone valerate 0.05%, fluocinonide 0.05%, and clobetasol propionate 0.05%. The best regrowth observed resulted from the use of clobetasol propionate 0.05%, giving full regrowth in 50% of those treated. Alopecia areata can occur at all ages and, thus, can be classified as both an acquired and a congenital disorder resulting in hair loss.

Tóm lược

The diagnosis was made clinically in all cases of congenital alopecia areata with follow-up from 3 to 5 years, and the best regrowth observed resulted from the use of clobetasol propionate, giving full regrowth in 50% of those treated.

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