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Oral minoxidil use in androgenetic alopecia and telogen effluvium.

Brittany Feaster, Toluwalashe Onamusi, Jerry E Cooley, Amy J McMichael
Other Archives of dermatological research 2023 16 atıf
PubMed DOI
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Study Design

Çalışma Türü
retrospective cohort
Örneklem Büyüklüğü
210
Süre
52 weeks
Müdahale
Oral minoxidil use in androgenetic alopecia and telogen effluvium. oral minoxidil 0.625–2.5 mg once daily
Karşılaştırıcı
Placebo
Etki Yönü
Positive
Yanlılık Riski
Moderate

Abstract

While current studies have supported oral minoxidil as a novel, adjunctive therapy in non-scarring forms of alopecia, there continues to be limited data on oral minoxidil for these conditions. To assess oral minoxidil use in the treatment of androgenetic alopecia and telogen effluvium, a multi-center, retrospective analysis was conducted in 105 adult patients treated for androgenetic alopecia and/or telogen effluvium with oral minoxidil (dose range 0.625-2.5 mg) once daily for ≥ 52 weeks, case matched by age (± 5 years) and gender with 105 controls with androgenetic alopecia and/or telogen effluvium who were not treated with oral minoxidil. 80 women (76.2%) with a mean age of 57.5 ± 13.56 (range 24-80) and 25 men (23.8%) with a mean age of 40.4 ± 13.79 (range 19-63) were included. Efficacy was evaluated based on provider assessment of clinical response and clinical photographic evaluation using a 3-point scale (worsening, stabilization, and improvement). 52.4% of patients demonstrated clinical improvement and 42.9% demonstrated stabilization. There was a significant difference in clinical response between the patient and control group, p < 0.001. Retrospective study design. These results suggest that oral minoxidil can be an effective treatment in androgenetic alopecia and telogen effluvium.

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