Medical treatment of male pattern alopecia (androgenic alopecia).

The causes and potential causes of androgenic alopecia in men and women are discussed. The scientific attempts at reversing this process are detailed including use of estrogen, thyroid, progesterone, and minoxidil. At present, the practical approach for the clinician is to ascertain in females that an androgen overproduction syndrome is not present. A therapeutic trial of topical progesterone at a 2%-5% concentration appears to be reasonable when the physician and patient appreciate the limitations of this approach.