Trace element levels in alopecia areata.

Yasmeen J Bhat, Sheikh Manzoor, A R Khan, Seema Qayoom

Other Indian journal of dermatology, venereology and leprology 2009 79 цитирований

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Study Design

Тип исследования: Case-Control
Размер выборки: 100

Вмешательство: Trace element levels in alopecia areata.
Препарат сравнения: Placebo
Направление эффекта: Negative
Риск систематической ошибки: Moderate

Abstract

BACKGROUND: Alopecia areata (AA) is a recurrent, nonscarring type of hair loss considered to be an autoimmune process. Though its etiopathology is not fully understood, there are claims that imbalance of trace elements may trigger the onset of AA. AIM: The aim of the present study was to assess the levels of zinc, copper, and magnesium in the serum of AA patients. METHODS: Fifty AA patients (34 men and 16 women), and fifty age and sex matched healthy control subjects were studied. Samples were analyzed using atomic absorption spectrometric methods. RESULTS: Serum zinc levels were significantly decreased (P < 0.05) in AA patients whose disease was extensive, prolonged, and resistant to treatment, whereas serum copper and magnesium levels showed insignificant rise compared to controls. CONCLUSION: We conclude that copper and magnesium levels are not altered in AA, but the decreased zinc levels found in our study may merit further investigation of the relationship.

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Trace element levels in alopecia areata.

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Study Design

Abstract

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