Congenital alopecia areata.
Study Design
- Tipo de Estudo
- Case Reports
- Tamanho da Amostra
- 4
- População
- Neonates/infants with congenital alopecia areata
- Duração
- 156 weeks
- Intervenção
- Congenital alopecia areata. Clobetasol propionate 0.05%, minoxidil 2%
- Comparador
- None
- Desfecho Primário
- Hair regrowth
- Direção do Efeito
- Positive
- Risco de Viés
- High
Abstract
Alopecia areata, the alleged autoimmune process leading to nonscarring hair loss, is not uncommon. It has been classified as an acquired cause of alopecia; however, recently it has been reported in the neonatal period. We report 4 cases of congenital alopecia areata with follow-up from 3 to 5 years. The diagnosis was made clinically in all cases. All patients had prolonged periods of quiescence of hair loss ranging from 6 to 24 months. Treatments used included minoxidil 2% and a range of topical steroids including hydrocortisone 1%, betamethasone valerate 0.05%, fluocinonide 0.05%, and clobetasol propionate 0.05%. The best regrowth observed resulted from the use of clobetasol propionate 0.05%, giving full regrowth in 50% of those treated. Alopecia areata can occur at all ages and, thus, can be classified as both an acquired and a congenital disorder resulting in hair loss.
Resumo Rápido
The diagnosis was made clinically in all cases of congenital alopecia areata with follow-up from 3 to 5 years, and the best regrowth observed resulted from the use of clobetasol propionate, giving full regrowth in 50% of those treated.
Used In Evidence Reviews
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