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New and Emerging Therapies for Alopecia Areata.

Aunna Pourang, Natasha Atanaskova Mesinkovska
Review Drugs 2020 33 인용
PubMed DOI
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Study Design

연구 유형
Review
대상 집단
Alopecia areata patients
중재
New and Emerging Therapies for Alopecia Areata. None
대조군
None
일차 결과
None
효과 방향
Negative
비뚤림 위험
Unclear

Abstract

Alopecia areata (AA) is an autoimmune condition that affects up to 2% of the general population. Currently available treatment options for AA are of limited efficacy and can be associated with adverse effects. The advancement in understanding of the genetic and molecular mechanisms of AA has led to the development of novel treatment options, with the Janus kinase (JAK) inhibitor class of drugs at the forefront of ongoing clinical trials. Platelet-rich plasma, fecal transplants, and cytokine-targeted therapy with ustekinumab and dupilumab have also been shown to regrow hair in patients with AA in individual case reports or small studies. Several other novel therapies have preliminary data or are being tested in clinical trials.

요약

Platelet-rich plasma, fecal transplants, and cytokine-targeted therapy with ustekinumab and dupilumab have also been shown to regrow hair in patients with AA in individual case reports or small studies.

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