What are the side effects of Folate?

Potential side effects include: Generally well tolerated, May mask vitamin B12 deficiency symptoms at high doses, Rare: abdominal cramps, insomnia.

Can folate supplementation support hair growth?

Folate (vitamin B9) plays a role in cell division and tissue growth, including hair follicle cells. Research suggests that low folate levels may be associated with premature graying and hair loss in some populations. A 2017 study in the Indian Journal of Dermatology found lower serum folate levels in people with premature hair graying compared to controls.

Should I take folate or folic acid for hair health?

Folate is the naturally occurring form of vitamin B9 found in foods, while folic acid is the synthetic form used in supplements. Both may support hair health by contributing to DNA synthesis and cell division. People with MTHFR gene variants may benefit from methylfolate (5-MTHF) rather than folic acid. Consult a healthcare provider for personalized guidance.

How much folate should I take for hair health?

The recommended dietary allowance (RDA) for folate is 400 mcg DFE (dietary folate equivalents) for adults. Hair-related studies have not established a specific supplemental dose for hair growth, though deficiency correction typically uses 400 to 1,000 mcg of folic acid daily. Research across 11 studies with 4,429 participants for nutritional deficiency hair loss is graded Limited (C), suggesting supplementation may help primarily when deficiency is confirmed.

How does folate help with hair growth?

Folate (vitamin B9) supports rapid cell division in hair follicle matrix cells during the anagen (active growth) phase. It is essential for DNA synthesis and methylation, which regulate gene expression in hair follicle stem cells. Research across 6 studies with 4,166 participants in telogen effluvium suggests folate deficiency may contribute to increased hair shedding. Adequate folate may help support normal follicle cell turnover.

Is low folate linked to hair loss?

Research suggests that folate deficiency may contribute to hair loss, particularly in telogen effluvium and nutritional deficiency contexts. Studies across 11 studies with 4,429 participants show a Limited (Grade C) association — folate deficiency is one of several micronutrient gaps that can disrupt normal hair cycling. Blood tests measuring serum folate or homocysteine levels can help determine whether deficiency is a contributing factor in your case.

Folate

vitamin

Also known as: Folic acid, Vitamin B9, 5-MTHF, Methylfolate

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'haircited.com'; const params = 'ingredient\u003Dfolate'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

About

Folate (vitamin B9) is essential for nucleotide synthesis and methylation reactions in rapidly dividing follicular keratinocytes. While severe folate deficiency can cause hair loss, research on supplementation for hair growth in non-deficient individuals is limited.

How It Works

Essential for nucleotide synthesis and methylation reactions in rapidly dividing follicular keratinocytes.

Evidence For Conditions

Condition	Grade	Studies	Participants
Telogen Effluvium	B	10	7126	View →
Nutritional Deficiency Hair Loss	F	11	4166	View →

Side Effects

Generally well tolerated
May mask vitamin B12 deficiency symptoms at high doses
Rare: abdominal cramps, insomnia

Drug & Supplement Interactions

Methotrexate (folate antagonist; consult physician)
Anticonvulsants (phenytoin, carbamazepine) may reduce folate levels
Sulfasalazine (reduces folate absorption)

Always inform your healthcare provider about all supplements you take.

Related Ingredients

Biotin Vitamin A Vitamin B12 Vitamin D Vitamin E

Quick Facts

Dosage: General: 400 mcg DFE/day
Forms: capsule tablet
Natural Sources: Leafy greens, Legumes, Asparagus, Citrus fruits, Fortified grains
Upper Limit: 1,000 mcg/day (synthetic folic acid)
Best Time: With meals for better absorption

Evidence Summary

Telogen Effluvium B

Nutritional Deficiency Hair Loss F

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.