Biotin
vitaminAlso known as: Vitamin B7, Vitamin H, Coenzyme R
About
Biotin (vitamin B7) is a water-soluble B-vitamin that serves as a cofactor for carboxylase enzymes involved in keratin production and fatty acid metabolism. While biotin deficiency clearly causes hair loss, supplementation in non-deficient individuals shows inconsistent results.
How It Works
Cofactor for carboxylase enzymes essential for keratin synthesis and fatty acid metabolism in hair follicles.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Nutritional Deficiency Hair Loss | B | 10 | 134 | View → |
| Telogen Effluvium | B | 9 | 484 | View → |
Side Effects
- May interfere with laboratory test results (troponin, thyroid panels)
- Rare skin rashes at high doses
- Mild gastrointestinal discomfort
- Potential acne breakouts at doses above 5,000 mcg
Drug & Supplement Interactions
- Anticonvulsants (carbamazepine, phenytoin) may reduce biotin levels
- Raw egg whites (avidin) bind biotin and reduce absorption
- Prolonged antibiotic use may deplete gut bacterial biotin synthesis
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.