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Randomized Controlled Trials

Gold-standard experimental studies with random treatment allocation.

Spironolactone versus Bicalutamide in female pattern hair loss: A randomised clinical trial.

Clinical and experimental dermatology 2026

Platelet-Rich Plasma Treatment for Endocrine-Induced Alopecia and Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Randomized, Controlled, Pilot Study.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2026

Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial.

The British journal of surgery 2025 10 citations

Effects of a cannabidiol/terpene formulation on sleep in individuals with insomnia: a double-blind, placebo-controlled, randomized, crossover study.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2025 6 citations

A Prospective and Comparative Study to Explore the Effects of Platelet-Rich Plasma in Hair Transplantation for Patients With Androgenetic Alopecia.

Journal of cosmetic dermatology 2025 5 citations

Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam.

Clinical, cosmetic and investigational dermatology 2025 4 citations

Hair regeneration in androgenetic alopecia using secretome of adipose-derived stem cells (ADSC) and minoxidil: a comparative study of three groups.

Archives of dermatological research 2025 3 citations

Efficacy and safety of twice- or thrice-weekly dutasteride versus daily finasteride in men with androgenetic alopecia: A randomized, investigator-blinded, active-controlled, parallel-group pilot study.

JAAD international 2025 3 citations

Effects of oral minoxidil on serum VEGF and hair regrowth in androgenetic alopecia.

Acta dermatovenerologica Alpina, Pannonica, et Adriatica 2025 2 citations

Efficacy and Safety of Low-Dose (0.2 mg) Dutasteride for Male Androgenic Alopecia: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase III Clinical Trial.

Annals of dermatology 2025 2 citations

Long-term use of dutasteride to treat androgenic alopecia in young men may lead to persistent abnormalities in semen parameters.

Clinical and experimental reproductive medicine 2025 2 citations

Analysing efficacy of low-dose oral minoxidil, topical minoxidil, and platelet-rich plasma with topical minoxidil combination in patients with androgenetic alopecia: a randomized controlled observer blinded trial.

Archives of dermatological research 2025 2 citations

Randomized controlled trial on the efficacy and safety of the combination therapy of topical 0.1% finasteride - 5% Minoxidil in male androgenetic alopecia.

Archives of dermatological research 2025 2 citations

Comparison of Safety and Efficacy of Topical Mometasone 0.1% Ointment, Calcipotriol 0.005% Ointment, and Tacrolimus 0.1% Ointment in Patients with Localized Alopecia Areata: A Triple-Arm Randomized Clinical Study.

Indian dermatology online journal 2025 1 citation

Dutasteride Infusion in Male Androgenetic Alopecia Using a Novel Drug Delivery Technique: MMP®.

Skin appendage disorders 2025 1 citation

Fractional CO2 Laser and Minoxidil in the Treatment of Alopecia Areata, A Comparative Study.

Lasers in surgery and medicine 2025 1 citation

Platelet-rich plasma for androgenetic alopecia: intradermal injection or microneedle delivery?

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 2025 1 citation

Intralesional Platelet-Rich Plasma Injection in Patients with Recalcitrant Alopecia Areata.

Sisli Etfal Hastanesi tip bulteni 2025

Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich Plasmain Alopecia Areaata.

International journal of trichology 2025

A Randomized, Double-Blind, Placebo and Active Controlled Phase II Study to Evaluate the Safety and Efficacy of Novel Dutasteride Topical Solution (0.01%, 0.02%, and 0.05% w/v) in Male Subjects With Androgenetic Alopecia.

Cureus 2025

Oral Minoxidil vs Topical Minoxidil for Male Androgenetic Alopecia: A Randomized Clinical Trial.

JAMA dermatology 2024 41 citations

Clinical efficacy and safety of low-dose oral minoxidil versus topical solution in the improvement of androgenetic alopecia: A randomized controlled trial.

Journal of cosmetic dermatology 2024 27 citations

Tolerability of long-term cannabidiol supplementation to healthy adult dogs.

Journal of veterinary internal medicine 2024 19 citations

Can supplementing vitamin B12 improve mental health outcomes?: a literature review.

British journal of community nursing 2024 9 citations

Comparative efficacy of 2% minoxidil alone against combination of 2% minoxidil and low-level laser therapy in female pattern hair loss-A randomized controlled trial in Chinese females.

Photodiagnosis and photodynamic therapy 2024 7 citations

Platelet-Rich Plasma: Advances and Controversies in Hair Restoration and Skin Rejuvenation.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2024 6 citations

Assessing the efficacy and quality of Life improvements of botulinum toxin type a with topical minoxidil versus topical minoxidil in male androgenetic alopecia: a randomized controlled trial.

Archives of dermatological research 2024 5 citations

Does a broad-spectrum cannabidiol supplement improve performance in a 10-min cycle ergometer performance-test?

European journal of sport science 2024 4 citations

Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in Treating Alopecia Areata: A Head-to-Head Assessment of Novel Approaches.

Cureus 2024 3 citations

Split-scalp pilot study to evaluate effectiveness of Minoxidil 0,5% MMP® versus Topical Minoxidil 5% in the treatment of Female Pattern Hair Loss.

Archives of dermatological research 2024 3 citations

Efficacy of Topical Finasteride 0.25% With Minoxidil 5% Versus Topical Minoxidil 5% Alone in Treatment of Male Pattern Androgenic Alopecia.

Journal of drugs in dermatology : JDD 2024 2 citations

The Role of 5% Minoxidil <em>versus</em> Platelet-Rich Plasma in Treatment of Alopecia Areata.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2024 2 citations

Comparison of Efficacy of Topical Betamethasone Dipropionate and Topical Minoxidil in Patients With Alopecia Areata.

Cureus 2024 2 citations

Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials.

Journal of Parkinson's disease 2024 1 citation

Intralesional vitamin D3 versus intralesional triamcinolone acetonoid in patchy alopecia areata: a comparative clinical and dermoscopic study.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 2024 1 citation

Micronutrient Gaps and Supplement Use in a Diverse Cohort of Pregnant Women.

Nutrients 2023 11 citations

Evaluation of the safety and efficacy of platelet-rich plasma in the treatment of female patients with chronic telogen effluvium: A randomised, controlled, double-blind, pilot clinical trial.

Indian journal of dermatology, venereology and leprology 2023 10 citations

Comparative evaluation of the efficacy of topical tacrolimus 0.03% and topical calcipotriol 0.005% mixed with betamethasone dipropionate versus topical clobetasol 0.05% in treatment of alopecia areata: A clinical and trichoscopic study.

Journal of cosmetic dermatology 2023 10 citations

Daily Folic Acid and/or Vitamin B12 Supplementation Between 6 and 30 Months of Age and Cardiometabolic Risk Markers After 6-7 Years: A Follow-Up of a Randomized Controlled Trial.

The Journal of nutrition 2023 6 citations

Effect of platelet counts and activator in platelet-rich plasma on the treatment of androgenetic alopecia, split-head comparison: A randomised, double-blind study.

Indian journal of dermatology, venereology and leprology 2023 6 citations

Platelet-Rich Plasma in Androgenetic Alopecia: Is It Really Worth the Hype?

International journal of trichology 2023 5 citations

Diphenylcyclopropenone and platelet-rich plasma in the management of severe or recalcitrant alopecia areata.

Journal of cosmetic dermatology 2023 3 citations

Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia areata: a clinical, dermoscopic and immunohistochemical study.

Archives of dermatological research 2023 3 citations

Therapeutic effects of topical cetirizine in the treatment of female pattern hair loss: a randomized controlled noninferiority trial.

Expert review of clinical pharmacology 2023 3 citations

Comparative Efficacy of Topical Minoxidil Alone Against Combination of Topical Minoxidil and Platelet Rich Plasma in Women with Female Pattern Hair Loss-A Pilot, Open Randomised Trial.

Indian journal of dermatology 2023 3 citations

Activated Platelet Rich Plasma versus Non-Activated Platelet Rich Plasma in the Treatment of Alopecia Areata.

Skin appendage disorders 2023 3 citations

Efficacy of Platelet-Rich Plasma in Males With Androgenetic Alopecia.

Cureus 2023 3 citations

Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial.

Journal of the European Academy of Dermatology and Venereology : JEADV 2022 96 citations

Randomized trial of electrodynamic microneedling combined with 5% minoxidil topical solution for treating androgenetic alopecia in Chinese males and molecular mechanistic study of the involvement of the Wnt/β-catenin signaling pathway.

The Journal of dermatological treatment 2022 35 citations

Effects of Cannabidiol on Exercise Physiology and Bioenergetics: A Randomised Controlled Pilot Trial.

Sports medicine - open 2022 34 citations

Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.

Journal of cosmetic dermatology 2022 23 citations

Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial.

Frontiers in medicine 2022 14 citations

Microneedling plus topical dutasteride solution for androgenetic alopecia: a randomized placebo-controlled study.

Journal of the European Academy of Dermatology and Venereology : JEADV 2022 11 citations

Randomized trial of microneedling combined with 2% minoxidil topical solution for the treatment of female pattern hair loss in a Chinese population.

Journal of cosmetic dermatology 2022 10 citations

Evaluating the Efficacy of Platelet Rich Plasma and 1550 nm Fractional Laser in Combination and Alone for the Management of Androgenetic Alopecia.

Journal of drugs in dermatology : JDD 2022 9 citations

Comparative study between topical methotrexate 1% gel and minoxidil 5% gel in the treatment of localized alopecia areata.

Dermatologic therapy 2022 7 citations

Effects of a Supplement Containing Cannabidiol (CBD) on Sedation and Ataxia Scores and Health.

Journal of equine veterinary science 2022 6 citations

Comparative Study Between Intralesional Injection Of Platelet Rich Plasma And Intra Lesional Triamcinolone For The Treatment Of Alopecia Areata.

Journal of Ayub Medical College, Abbottabad : JAMC 2022 4 citations

Combination of platelet-rich plasma and platelet gel in treatment of resistance androgenic alopecia: A case series study.

Journal of cosmetic dermatology 2022 3 citations

A new combination of molecules for the treatment of androgenetic alopecia and telogen effluvium: a double-blind randomized, monocentric, placebo-controlled study.

Italian journal of dermatology and venereology 2022 2 citations

Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.

Ophthalmology 2021 134 citations

Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.

Journal of ethnopharmacology 2021 58 citations

Microneedling in androgenetic alopecia; comparing two different depths of microneedles.

Journal of cosmetic dermatology 2021 39 citations

Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study.

The journal of obstetrics and gynaecology research 2021 38 citations

Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: A randomized comparative trial.

Journal of cosmetic dermatology 2021 29 citations

A randomized clinical trial on therapeutic effects of 0.25 mg oral minoxidil tablets on treatment of female pattern hair loss.

Dermatologic therapy 2021 27 citations

Comparison of low-level light therapy and combination therapy of 5% minoxidil in the treatment of female pattern hair loss.

Lasers in medical science 2021 17 citations

Evaluation of platelet-rich plasma on hair regrowth and lesional T-cell cytokine expression in alopecia areata: A randomized observer-blinded, placebo-controlled, split-head pilot study.

Journal of the American Academy of Dermatology 2021 14 citations

Effects of different types of zinc supplement on the growth, incidence of diarrhea, immune function, and rectal microbiota of newborn dairy calves.

Journal of dairy science 2020 58 citations

Platelet-rich Plasma for Androgenetic Alopecia Treatment: A Randomized Placebo-controlled Pilot Study.

Acta dermato-venereologica 2020 31 citations

State of the art review: oral and nasal vitamin B12 therapy in the elderly.

QJM : monthly journal of the Association of Physicians 2020 28 citations

Combination of photodynamic therapy with 5-aminolaevulinic acid and microneedling in the treatment of alopecia areata resistant to conventional therapies: our experience with 41 patients.

Clinical and experimental dermatology 2020 27 citations

Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Area Celsi: A Randomized Double-Blinded Parallel-Group Study.

Dermatology and therapy 2020 26 citations

Comparative Evaluation of Therapeutic Efficacy of Intralesional Injection of Triamcinolone Acetonide versus Intralesional Autologous Platelet-rich Plasma Injection in Alopecia Areata.

Journal of cutaneous and aesthetic surgery 2020 21 citations

A randomized, placebo and active controlled, split scalp study to evaluate the efficacy of platelet-rich plasma in patchy alopecia areata of the scalp.

Dermatologic therapy 2020 18 citations

Platelet-Rich Plasma and Stem Cells for Hair Growth: A Review of the Literature.

Aesthetic surgery journal 2020 13 citations

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.

Cureus 2019 101 citations

Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women: a 24-week, randomized, double-blind, sham device-controlled trial.

Lasers in medical science 2019 88 citations

Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study.

American journal of clinical dermatology 2019 67 citations

A Study to Compare the Efficacy of Platelet-rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia.

International journal of trichology 2019 41 citations

Efficacy of platelet-rich plasma in androgenetic alopecia patients.

Journal of cosmetic dermatology 2019 30 citations

The effect of platelet-rich plasma injection in the treatment of androgenetic alopecia.

Journal of cosmetic dermatology 2019 24 citations

Randomized controlled trial on a PRP-like cosmetic, biomimetic peptides based, for the treatment of alopecia areata.

The Journal of dermatological treatment 2019 16 citations

Platelet rich plasma for the management of hair loss: Better alone or in combination?

Journal of cosmetic dermatology 2019 13 citations

A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia.

Journal of the European Academy of Dermatology and Venereology : JEADV 2018 94 citations

Platelets rich plasma versus minoxidil 5% in treatment of alopecia areata: A trichoscopic evaluation.

Dermatologic therapy 2017 107 citations

A Comparative Study of Microneedling with Platelet-rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia.

International journal of trichology 2017 71 citations

Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study.

Indian journal of dermatology, venereology and leprology 2017 71 citations

Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy).

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2017 43 citations

An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia.

Skin pharmacology and physiology 2017 42 citations

Hypoglycemic and Hypolipidemic Effects of Leucine, Zinc, and Chromium, Alone and in Combination, in Rats with Type 2 Diabetes.

Biological trace element research 2017 35 citations

Alopecia and platelet-derived therapies.

Stem cell investigation 2017 27 citations

Long-term safety and efficacy of dutasteride in the treatment of male patients with androgenetic alopecia.

The Journal of dermatology 2016 54 citations

Minoxidil dose response study in female pattern hair loss patients determined to be non-responders to 5% topical minoxidil.

Journal of biological regulators and homeostatic agents 2016 30 citations

Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study.

Journal of drugs in dermatology : JDD 2016 22 citations

[Therapeutic effects of zinc supplement as adjunctive therapy in infants and young children with rotavirus enteritis].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2016 9 citations

A Phase III, Multicenter, Parallel-Design Clinical Trial to Compare the Efficacy and Safety of 5% Minoxidil Foam Versus Vehicle in Women With Female Pattern Hair Loss.

Journal of drugs in dermatology : JDD 2016

Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial.

Skinmed 2015 81 citations

Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study.

Journal of drugs in dermatology : JDD 2015 50 citations

Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, sham device-controlled, double-blind study.

American journal of clinical dermatology 2014 184 citations