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MSM untuk Penipisan Rambut Terkait Usia

B

Berdasarkan 2 studi dengan 20 peserta secara total. 2/2 studi menunjukkan efek positif.

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            B

        

        

            
Kesimpulan

            
            
MSM shows very early and limited promise for hair thinning based on animal studies, but there are no human clinical trials to support its use for this purpose.

            
            
            
    
                
                
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                    Only 2 studies exist, both showing positive results but neither involving human participants
                
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                    MSM is a sulfur-rich compound that theoretically supports keratin and collagen formation
                
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                    One animal study showed potential benefits when MSM was combined with minoxidil
                
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                    Human clinical trials are needed before MSM can be recommended for age-related hair thinning
                
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Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                n=791
                
                
                
                Double-blind
                
            

            
                Daily Folic Acid and/or Vitamin B12 Supplementation Between 6 and 30 Months of Age and …
            
            

                
                Dose: 1.8 μg
                
                
                vs: placebo
                
                
                Outcome: Cardiometabolic risk markers
                
                
                Efek: None
                
                
                None
                
            

            
            
Populasi: Children aged 6-30 months (follow-up at 6-7y)

            
        

        
        

            

                
                    Meta-Analysis
                
                
                
                
            

            
                Associations between Folate and Vitamin B12 Levels and Inflammatory Bowel Disease: A Meta-Analysis.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Serum folate and B12 levels in IBD vs …
                
                
                Efek: None
                
                
                None
                
            

            
            
Populasi: IBD patients vs healthy controls

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
Studi

    

    

        
791

        
Peserta

    

    

        
            
            ↔
            
        
        
Mixed

    

    

        B

        
Peringkat

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Daily Folic Acid and/or Vitamin B12 Supplementation Between 6 and 30 Months of Age and Cardiometabolic Risk Markers After 6-7 …
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        The Journal of …
                        2023
                        
                        6 sitasi
                        
                    

                

                
                

                    

                        
                            Associations between Folate and Vitamin B12 Levels and Inflammatory Bowel Disease: A Meta-Analysis.
                        
                        
                            
                                Meta-Analysis
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2017
                        
                        123 sitasi
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosis yang Umum Digunakan

                

                    
                    

                        
hairloss:

                        
1,000-3,000 mg/day

                    

                    
                

                
                

                    Batas atas: Not established
                

                
            

            

            
            

                
Dosis yang Diteliti dalam Penelitian

                

                    

                        
                            

                                Dosis
                                Durasi
                                Efek
                                N
                            

                        
                        
                            
                            

                                1.8 μg
                                --
                                
                                    
                                    Positive
                                    
                                
                                791
                            

                            
                            

                                None
                                --
                                
                                    
                                    Neutral
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Waktu terbaik diminum: Divided into 2-3 doses throughout the day with meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efek Samping yang Dilaporkan

                    
    
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
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                            ⚠
                            Headache
                        
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                            ⚠
                            Insomnia at high doses
                        
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                            ⚠
                            Skin rash (uncommon)
                        
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Interaksi yang Diketahui

                    
    
                        
                        
  • 
                            ●
                            Blood thinners (MSM may have mild anticoagulant properties)
                        
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  • 
                            ●
                            No other significant drug interactions established
                        
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                        Asupan atas yang dapat ditoleransi: Not established
                    

                

                
            

            

                Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does MSM help with Penipisan Rambut Terkait Usia?
            
        
        

            Based on 2 studies with 791 participants, there is moderate evidence from clinical studies that MSM may support Penipisan Rambut Terkait Usia management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much MSM should I take for Penipisan Rambut Terkait Usia?
            
        
        

            Studies have used various dosages. A commonly studied range is 1,000-3,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of MSM?
            
        
        

            Reported side effects may include Mild gastrointestinal discomfort, Headache, Insomnia at high doses, Skin rash (uncommon). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for MSM and Penipisan Rambut Terkait Usia?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 2 peer-reviewed studies with 791 total participants. The overall direction of effect is mixed.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

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        Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.