Zat Besi untuk Kerontokan Rambut Akibat Defisiensi Zat Besi

Q: Does Zat Besi help with Kerontokan Rambut Akibat Defisiensi Zat Besi?

Based on 73 studies with 30,034 participants, there is strong evidence from multiple clinical trials that Zat Besi may support Kerontokan Rambut Akibat Defisiensi Zat Besi management. Our evidence grade is A (Strong Evidence).

Q: How much Zat Besi should I take for Kerontokan Rambut Akibat Defisiensi Zat Besi?

Studies have used various dosages. A commonly studied range is 18 mg/day (women). Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Zat Besi?

Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Zat Besi and Kerontokan Rambut Akibat Defisiensi Zat Besi?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 73 peer-reviewed studies with 30,034 total participants. The overall direction of effect is mixed.

Berdasarkan 73 studi (4 meta-analyses) dengan 30,034 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

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Kesimpulan

Iron deficiency is clearly linked to hair loss, and correcting a genuine deficiency may support hair regrowth, but iron supplementation is not universally effective for all types of hair loss.

73 studies across 30,034 participants provide extensive evidence on the iron-hair loss connection
Low serum ferritin levels are frequently observed in patients with hair loss
Supplementation appears most beneficial when a true iron deficiency is documented
Iron supplementation without confirmed deficiency may not improve hair outcomes and can carry risks

Key Study Findings

review

[Restless leg syndrome. Diagnosis and treatment].

Dose: various vs: Placebo Efek: None None

case-control n=90

Restless Leg Syndrome and Association with Serum NT Pro-CNP.

Dose: None vs: Placebo Efek: NT pro-CNP significantly lower in RLS vs controls; sensitivity 80%, specificity 88.9%; serum iron lo None

Review

Iron Metabolism and the Role of Iron Therapy in Pediatric Restless Leg Syndrome.

Dose: None vs: Placebo Efek: None None

cross-sectional n=150

Prevalence of Restless Leg Syndrome and Its Association With Iron Deficiency in Patients With Chronic …

Dose: None vs: Placebo Efek: RLS prevalence 42%; serum ferritin lower in RLS (88.4 vs 126.7 ng/mL); TSAT lower (16.3% vs 22.1%); p < 0.01

review

Restless Leg Syndrome and Pregnancy.

Dose: iron supplementation, folate, dopamine agonists (non-pharmacological and pharmacological) vs: Placebo Efek: None None

cross-sectional study n=100

Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.

Dose: not applicable (observational; serum ferritin measured) vs: Placebo Efek: mean ferritin 24.30 vs 44.78 ng/mL < 0.001

Key Statistics

Studi

30034

Peserta

↔

Mixed

Peringkat

Referenced Papers

[Restless leg syndrome. Diagnosis and treatment]. Review

Revista de neurologia None 8 sitasi

Restless Leg Syndrome and Association with Serum NT Pro-CNP. Other

Neurology India 2026

Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience. Other

Journal of cosmetic … 2025 4 sitasi

Iron Metabolism and the Role of Iron Therapy in Pediatric Restless Leg Syndrome. Review

Sleep medicine clinics 2025 2 sitasi

Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium. Other

Cureus 2025

Optimizing Restless Legs Syndrome Care: Integrating Rehabilitation into Multimodal Management. Review

JPMA. The Journal … 2025

Prevalence of Restless Leg Syndrome and Its Association With Iron Deficiency in Patients With Chronic Kidney Disease: A Cross-Sectional Observational … Other

Cureus 2025

Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases. Other

International journal of … 2025

Restless Leg Syndrome and Pregnancy. Review

Southern medical journal 2025

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid … Other

Journal of cosmetic … 2024 7 sitasi

Iron Deficiency and Restless Sleep/Wake Behaviors in Neurodevelopmental Disorders and Mental Health Conditions. Other

Nutrients 2024 7 sitasi

Post Covid telogen effluvium: the diagnostic value of serum ferritin biomarker and the preventive value of dietary supplements. a case … Other

Archives of dermatological … 2024 5 sitasi

Iron Supplementation May Improve the Patient's Level of Satisfaction in Not-Low-Ferritin Telogen Effluvium: A Real-Life Observational Study. Other

Indian journal of … 2024 4 sitasi

Brain Iron Dysregulation in Iron Deficiency Anemia-Related Restless Leg Syndrome Revealed by Neuron-Derived Extracellular Vesicles: A Case-Control Study. Other

Annals of neurology 2024 3 sitasi

Iron deficiency-related symptoms in non-anemic whole blood donors. Other

Transfusion 2024 2 sitasi

Clinical efficacy and safety of IV ferric carboxymaltose in restless legs syndrome: A meta-analysis of 537 patients. Meta-Analysis

Sleep medicine 2024 1 sitasi

Evaluation of the relationship of digital phototrichogram findings of patients with diffuse hair loss with blood TSH, ferritin and vitamin … Other

Northern clinics of … 2024 1 sitasi

Intersecting Pathways: Treating Cocaine Withdrawal and Restless Leg Syndrome with Iron and Buproprion. Case Report

Healthcare (Basel, Switzerland) 2024

Restless Legs Syndrome in Chronic Kidney Disease- a Systematic Review. Systematic Review

Tremor and other … 2023 32 sitasi

Restless leg syndrome in patients with chronic kidney disease: a hospital-based study from Upper Egypt. Other

The International journal … 2023 14 sitasi

Etiology, management, and outcomes of pediatric telogen effluvium: A single-center study in the United States. Other

Pediatric dermatology 2023 9 sitasi

The genetic etiology of periodic limb movement in sleep. Meta-Analysis

Sleep 2023 8 sitasi

Complementary and Integrative Approaches to Sleep Disorders in Children. Review

Child and adolescent … 2023 5 sitasi

Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center. Other

Dermatology practical & … 2023 4 sitasi

The incidence, complications, and treatment of iron deficiency in pregnancy. Review

European journal of … 2022 109 sitasi

Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium. Other

Journal of cosmetic … 2022 22 sitasi

Exploration of restless legs syndrome under the new concept: A review. Review

Medicine 2022 15 sitasi

Behavioral sleep medicine-The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental … Review

Frontiers in psychiatry 2022 8 sitasi

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom? Other

Turkish journal of … 2022 8 sitasi

Evaluation of MCV/RDW Ratio and Correlations With Ferritin in Telogen Effluvium Patients. Other

Dermatology practical & … 2022 6 sitasi

Does Dexmedetomidine Improve or Worsen Restless Leg Syndrome under Sedation: A Case Report and Extensive Review. Case Report

Case reports in … 2022 3 sitasi

The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women. Other

Cureus 2022 3 sitasi

Restless Leg Syndrome and Sleep Disorders in Patients with Rheumatoid Arthritis and Its Relation with Anemia Parameters. Other

Acta medica (Hradec … 2021 13 sitasi

Diagnostic and Treatment Considerations in Restless Legs Syndrome Complicated by Diabetic Neuropathy. Review

Current diabetes reports 2021 5 sitasi

The role of iron repletion in adult iron deficiency anemia and other diseases. Review

European journal of … 2020 137 sitasi

Comorbidities in alopecia areata: A systematic review and meta-analysis. Meta-Analysis

Journal of the … 2019 189 sitasi

Neurologic conditions and disorders of uremic syndrome of chronic kidney disease: presentations, causes, and treatment strategies. Review

Expert review of … 2019 123 sitasi

Restless legs syndrome and iron deficiency in adults with attention-deficit/hyperactivity disorder. Other

Sleep 2019 33 sitasi

NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. Observational

Journal of cosmetic … 2019 25 sitasi

Prevalence of Nutritional Deficiencies in Hair Loss among Indian Participants: Results of a Cross-sectional Study. Other

International journal of … 2017 43 sitasi

Changes of serum trace elements level in patients with alopecia areata: A meta-analysis. Meta-Analysis

The Journal of … 2017 31 sitasi

Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers. Other

Journal of renal … 2017 26 sitasi

Vitamin and Mineral Deficiencies in Patients With Telogen Effluvium: A Retrospective Cross-Sectional Study. Other

Journal of drugs … 2016 56 sitasi

Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other

International journal of … 2016 28 sitasi

Clinicoepidemiological Observational Study of Acquired Alopecias in Females Correlating with Anemia and Thyroid Function. Other

Dermatology research and … 2016 26 sitasi

Insomnia and Restless Leg Syndrome in Patients Undergoing Chronic Hemodialysis in Rafsanjan Ali Ibn Abitaleb Hospital. Other

Nephro-urology monthly 2016 21 sitasi

Importance of donor history of restless leg syndrome and pica to asses iron deficiency. Other

Transfusion and apheresis … 2016 10 sitasi

Non-invasive method distinguishes chronic telogen effluvium from mild female pattern hair loss: clinicopathological correlation. Other

International journal of … 2016 6 sitasi

Trichotillomania: Bizzare Patern of Hair Loss at 11-Year-old Girl. Case Report

Acta dermatovenerologica Croatica … 2016 6 sitasi

Restless Leg Syndrome/Willis-Ekbom disease in women with iron deficiency anemia. Other

Ideggyogyaszati szemle 2016 6 sitasi

Asthma as a disruption in iron homeostasis. Review

Biometals : an … 2016

Restless Leg Syndrome/Willis-Ekbom Disease Pathophysiology. Review

Sleep medicine clinics 2015 158 sitasi

A Hospital-based Study to Determine Causes of Diffuse Hair Loss in Women. Other

Journal of clinical … 2015 41 sitasi

Response to intravenous iron in patients with iron deficiency anemia (IDA) and restless leg syndrome (Willis-Ekbom disease). Other

Sleep medicine 2014 58 sitasi

Disorders of heavy metals. Review

Handbook of clinical … 2014 52 sitasi

Restless leg syndrome: a neglected diagnosis. Review

Nephro-urology monthly 2014 43 sitasi

Acute telogen effluvium onset event is associated with the presence of female androgenetic alopecia: potential therapeutic implications. Other

Dermatologic therapy 2014 13 sitasi

New treatment options for the management of restless leg syndrome. Review

The Journal of … 2014 7 sitasi

Telogen effluvium as the first symptom of Crohn's disease in a child. Case Report

Annals of gastroenterology 2014 5 sitasi

Is TrichoScan a new diagnostic method for diffuse hair loss? Other

Turkish journal of … 2014 5 sitasi

Serum ferritin and vitamin d in female hair loss: do they play a role? Other

Skin pharmacology and … 2013 127 sitasi

The diet factor in attention-deficit/hyperactivity disorder. Review

Pediatrics 2012 205 sitasi

ADMET considerations for restless leg syndrome drug treatments. Review

Expert opinion on … 2012 6 sitasi

Iron deficiency: beyond anemia. Review

Indian journal of … 2011 75 sitasi

Iron deficiency in female pattern hair loss, chronic telogen effluvium, and control groups. Other

Journal of the … 2010 94 sitasi

Diffuse hair loss in an adult female: approach to diagnosis and management. Review

Indian journal of … 2009 109 sitasi

Hyperferritinemia in autoimmunity. Review

The Israel Medical … 2008 61 sitasi

Nonhematological benefits of iron. Review

American journal of … 2007 61 sitasi

The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. Review

Journal of the … 2006 255 sitasi

Medical treatment of noncicatricial alopecia. Review

Seminars in cutaneous … 2006 23 sitasi

Decreased serum ferritin is associated with alopecia in women. Other

The Journal of … 2003 222 sitasi

Iron, brain and restless legs syndrome. Other

Sleep medicine reviews 2001 48 sitasi

Management of hair loss in women. Review

Dermatologic clinics 1993 38 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 18 mg/day (women)
deficiency:: 65-200 mg elemental iron/day

Batas atas: 45 mg/day

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
various	--	Positive	--
None	--	Positive	90
None	--	Positive	--
None	--	Positive	150
iron supplementation, folate, dopamine agonists (non-pharmacological and pharmacological)	--	Positive	--
not applicable (observational; serum ferritin measured)	--	Negative	100
None	--	Neutral	113
None	--	Neutral	2851

Waktu terbaik diminum: On an empty stomach with vitamin C for best absorption; take 2 hours apart from calcium

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Constipation (most common)
⚠ Nausea and stomach cramps
⚠ Dark or black stools
⚠ Iron overload with excessive supplementation (hemochromatosis risk)

Interaksi yang Diketahui

● Calcium supplements and dairy (reduce iron absorption by 50-60%)
● Proton pump inhibitors (omeprazole) and H2 blockers reduce absorption
● Tetracycline and quinolone antibiotics (mutual absorption reduction)
● Levothyroxine (iron reduces thyroid hormone absorption)

Asupan atas yang dapat ditoleransi: 45 mg/day

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Zat Besi help with Kerontokan Rambut Akibat Defisiensi Zat Besi?

Based on 73 studies with 30,034 participants, there is strong evidence from multiple clinical trials that Zat Besi may support Kerontokan Rambut Akibat Defisiensi Zat Besi management. Our evidence grade is A (Strong Evidence).

How much Zat Besi should I take for Kerontokan Rambut Akibat Defisiensi Zat Besi?

Studies have used various dosages. A commonly studied range is 18 mg/day (women). Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Zat Besi?

Reported side effects may include Constipation (most common), Nausea and stomach cramps, Dark or black stools, Iron overload with excessive supplementation (hemochromatosis risk). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Zat Besi and Kerontokan Rambut Akibat Defisiensi Zat Besi?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 73 peer-reviewed studies with 30,034 total participants. The overall direction of effect is mixed.

Related Evidence

Bahan lain untuk Kerontokan Rambut Akibat Defisiensi Zat Besi

L-Lysine D

Zat Besi untuk kondisi lain

Telogen Effluvium B Kerontokan Rambut Pascapersalinan D

Kesimpulan Singkat

Berdasarkan 73 studi (4 meta-analyses) dengan 30,034 peserta secara total. Hasil bervariasi di antara studi-studi tersebut.

Evidence Strength92%

High confidence

Rincian Studi

RCT (0)Meta (4)Other (69)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk Kerontokan Rambut Akibat Defisiensi Zat Besi

Pelajari Lebih Lanjut

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.