Combined Diet and Supplementation Therapy Resolves Alopecia Areata in a Paediatric Patient: A Case Study.
Study Design
- अध्ययन प्रकार
- Case report
- नमूना आकार
- 1
- अवधि
- 20 weeks
- हस्तक्षेप
- Combined Diet and Supplementation Therapy Resolves Alopecia Areata in a Paediatric Patient: A Case Study. Multi-nutrient supplement, zinc sulfate, fish oil with vitamin D; diet rich in vitamins A and D, zin
- तुलनित्र
- Placebo
- प्रभाव की दिशा
- Positive
- पूर्वाग्रह का जोखिम
- High
Abstract
Alopecia areata (AA) is a common autoimmune condition resulting in spot baldness and, rarely, more extensive hair loss. There is an association between both the incidence and the severity of AA and several micronutrients, including vitamin D and zinc. This case reports an eight-year-old male diagnosed with AA and treated with a diet and supplemental regimen based on unrefined foods, rich in vitamins A and D, zinc, and supplemented with a multi-nutrient, zinc sulfate, and fish oil with vitamin D. Complete remission of AA was achieved within five months.
Full Text
Figures
Figure 1
Clinical timeline or treatment protocol for the combined diet and supplementation therapy that resolved alopecia areata in a pediatric case.
diagram
Figure 2
Clinical photographs showing progressive hair regrowth during the dietary and supplementation intervention for the pediatric alopecia areata patient.
photograph
Figure 3
Final outcome photographs demonstrating complete resolution of alopecia areata following the combined dietary and supplement therapy approach.
photographTables
Table 1
| Amount provided in the supplements | Total supplemental dose per day | |
| Vitamin A (μg RE) | Multi: 400 | 400 |
| Vitamin D3 (μg) | Multi: 10, Fish oil: 12.5 | 22.5 (900 iu) |
| Zinc (mg) | Multi: 6, Zinc drops: 4 | 10 |
| Omega 3 fatty acids (mg) | Fish oil: DHA – 273, EPA – 410 | 683 (total n-3 fatty acids) |
Table 2
| Amount provided in the multi-nutrient | % RDI | |
| Vitamin A | 400 μg RE | 63 |
| Thiamin (B1) | 2.2 mg | 244 |
| Riboflavin (B2) | 3.4 mg | 354 |
| Vitamin B3 | 10 mg | 81 |
| Pantothenic acid | 5 mg | 109 |
| Vitamin B6 | 1.6 mg | 160 |
| Folate | 200 μg | 67 |
| Vitamin B12 | 5 μg | 278 |
| Vitamin C | 100 mg | 261 |
| Vitamin D3 | 10 μg | 200 |
| Vitamin E | 10 mg TE | 122 |
| Vitamin K | 80 μg | 178 |
| Biotin | 60 μg | 280 |
| Calcium | 206 mg | 21 |
| Magnesium | 50 mg | 18 |
| Zinc | 6 mg | 83 |
| Iron | 1.4 mg | 13 |
| Manganese | 1 mg | 34 |
| Copper | 0.3 mg | 25 |
| Selenium | 21 μg | 40 |
| Chromium | 20 μg | 83 |
| Iodine | 75 μg | 63 |
References
- Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis J Am Acad Dermatol, 2020
- Alopecia areata: a review of disease pathogenesis Br J Dermatol, 2018
- Alopecia areata: a comprehensive review of pathogenesis and management Clin Rev Allergy Immunol, 2018
- Oxidative stress in alopecia areata: a systematic review and meta-analysis Int J Dermatol, 2020
- Serum zinc reference intervals and its relationship with dietary, functional, and biochemical indicators in 6- to 9-year-old healthy children Food Nutr Res, 2016
- What is the optimal vitamin D status for health? Prog Biophys Mol Biol, 2006
- The role of micronutrients in alopecia areata: A review Am J Clin Dermatol, 2017
- Vitamin D deficiency in alopecia areata Br J Dermatol, 2014
- Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis J Eur Acad Dermatol Venereol, 2018
- Serum vitamin D level is related to disease severity in pediatric alopecia areata J Cosmet Dermatol, 2018
- An investigation of vitamin D status in alopecia areata Clin Exp Med, 2018
- Vitamin D receptor gene polymorphisms are not associated with alopecia areata Int J Dermatol, 2007
- Assessment of vitamin D receptors in alopecia areata and androgenetic alopecia J Cosmet Dermatol, 2016
- Correlation of vitamin D and vitamin D receptor expression in patients with alopecia areata: a clinical paradigm Int J Dermatol, 2018
- Evaluation of serum zinc level in patients with newly diagnosed and resistant alopecia areata Int J Dermatol, 2016
- Analysis of serum zinc and copper levels in alopecia areata Ann Dermatol, 1997
- Determination of plasma zinc values in patients with alopecia areata Ann Ital Dermatol Sifilogr, 1990
- Serum zinc level in alopecia areata patients: a cross-sectional study Dermatol Cosmet, 2012
- Zinc aspartate, biotin and clobetasol propionate in the treatment of alopecia areata in childhood J Eur Acad Dermatol Venereol, 1997
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