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Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives.

Michael R Hamblin
Other Clinical, cosmetic and investigational dermatology 2019 41 उद्धरण
PubMed DOI
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Study Design

अध्ययन प्रकार
Review
हस्तक्षेप
Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives. Low-level laser/light therapy (various devices and dosimetry)
तुलनित्र
Placebo
प्रभाव की दिशा
Positive
पूर्वाग्रह का जोखिम
Unclear

Abstract

Photobiomodulation (PBM) or low-level laser therapy was discovered over 50 years ago, when Mester in Hungary observed regrowth of hair in mice when irradiated with a ruby laser. At the present time, several different PBM devices are marketed to assist with hair regrowth in alopecia patients. This review covers the three main types of alopecia (androgenetic, areata, and chemotherapy-induced), and discusses the mechanism of action of PBM for each disease. The different devices used (mostly low powered red laser diodes), dosimetry, animal models, and clinical trials are summarized. Criteria for patient selection are outlined. Finally a perspectives section looks forward to the future.

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