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Alopecia areata: pathogenesis and treatment.

A J Mitchell, E A Krull
Other Journal of the American Academy of Dermatology 1984 122 citations
PubMed DOI
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Study Design

Type d'étude
Review
Population
alopecia patients
Intervention
Alopecia areata: pathogenesis and treatment. None
Comparateur
None
Critère de jugement principal
immune function
Direction de l'effet
Mixed
Risque de biais
Unclear

Abstract

Although its etiology remains unknown, evidence has accumulated to support an autoimmune pathogenesis for alopecia areata. Our review summarizes the immunologic data and also examines the role of genetics, atopy, and psychologic stress in this disorder. Until etiology is better understood, treatments for alopecia areata are likely to remain palliative. Nevertheless, newer therapies such as photochemotherapy, topical immunotherapy, and perhaps systemic immunotherapy (e.g., inosiplex) offer new hope for patients with extensive disease.

En bref

A review summarizes the immunologic data and also examines the role of genetics, atopy, and psychologic stress in this disorder, finding that newer therapies such as photochemotherapy, topical immunotherapy, and perhaps systemic immunotherapy offer new hope for patients with extensive disease.

Used In Evidence Reviews

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