Combined Diet and Supplementation Therapy Resolves Alopecia Areata in a Paediatric Patient: A Case Study.

Cliff J Harvey

Case Report Cureus 2020 5 citations

<\/script>\n

`; }, get iframeSnippet() { const domain = 'haircited.com'; const params = 'pmid\u003D33304703'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Study Design

Type d'étude: Case report
Taille de l'échantillon: 1
Durée: 20 weeks

Intervention: Combined Diet and Supplementation Therapy Resolves Alopecia Areata in a Paediatric Patient: A Case Study. Multi-nutrient supplement, zinc sulfate, fish oil with vitamin D; diet rich in vitamins A and D, zin
Comparateur: Placebo
Direction de l'effet: Positive
Risque de biais: High

Abstract

Alopecia areata (AA) is a common autoimmune condition resulting in spot baldness and, rarely, more extensive hair loss. There is an association between both the incidence and the severity of AA and several micronutrients, including vitamin D and zinc. This case reports an eight-year-old male diagnosed with AA and treated with a diet and supplemental regimen based on unrefined foods, rich in vitamins A and D, zinc, and supplemented with a multi-nutrient, zinc sulfate, and fish oil with vitamin D. Complete remission of AA was achieved within five months.

Full Text

PDF

Loading PDF...

Figures

Figure 1

Clinical timeline or treatment protocol for the combined diet and supplementation therapy that resolved alopecia areata in a pediatric case.

diagram

Figure 2

Clinical photographs showing progressive hair regrowth during the dietary and supplementation intervention for the pediatric alopecia areata patient.

photograph

Figure 3

Final outcome photographs demonstrating complete resolution of alopecia areata following the combined dietary and supplement therapy approach.

photograph

Tables

Table 1

	Amount provided in the supplements	Total supplemental dose per day
Vitamin A (μg RE)	Multi: 400	400
Vitamin D3 (μg)	Multi: 10, Fish oil: 12.5	22.5 (900 iu)
Zinc (mg)	Multi: 6, Zinc drops: 4	10
Omega 3 fatty acids (mg)	Fish oil: DHA – 273, EPA – 410	683 (total n-3 fatty acids)

Table 2

	Amount provided in the multi-nutrient	% RDI
Vitamin A	400 μg RE	63
Thiamin (B1)	2.2 mg	244
Riboflavin (B2)	3.4 mg	354
Vitamin B3	10 mg	81
Pantothenic acid	5 mg	109
Vitamin B6	1.6 mg	160
Folate	200 μg	67
Vitamin B12	5 μg	278
Vitamin C	100 mg	261
Vitamin D3	10 μg	200
Vitamin E	10 mg TE	122
Vitamin K	80 μg	178
Biotin	60 μg	280
Calcium	206 mg	21
Magnesium	50 mg	18
Zinc	6 mg	83
Iron	1.4 mg	13
Manganese	1 mg	34
Copper	0.3 mg	25
Selenium	21 μg	40
Chromium	20 μg	83
Iodine	75 μg	63

References

Epidemiology of alopecia areata, ophiasis, totalis, and universalis: A systematic review and meta-analysis J Am Acad Dermatol, 2020
Alopecia areata: a review of disease pathogenesis Br J Dermatol, 2018
Alopecia areata: a comprehensive review of pathogenesis and management Clin Rev Allergy Immunol, 2018
Oxidative stress in alopecia areata: a systematic review and meta-analysis Int J Dermatol, 2020
Serum zinc reference intervals and its relationship with dietary, functional, and biochemical indicators in 6- to 9-year-old healthy children Food Nutr Res, 2016
What is the optimal vitamin D status for health? Prog Biophys Mol Biol, 2006
The role of micronutrients in alopecia areata: A review Am J Clin Dermatol, 2017
Vitamin D deficiency in alopecia areata Br J Dermatol, 2014
Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis J Eur Acad Dermatol Venereol, 2018
Serum vitamin D level is related to disease severity in pediatric alopecia areata J Cosmet Dermatol, 2018
An investigation of vitamin D status in alopecia areata Clin Exp Med, 2018
Vitamin D receptor gene polymorphisms are not associated with alopecia areata Int J Dermatol, 2007
Assessment of vitamin D receptors in alopecia areata and androgenetic alopecia J Cosmet Dermatol, 2016
Correlation of vitamin D and vitamin D receptor expression in patients with alopecia areata: a clinical paradigm Int J Dermatol, 2018
Evaluation of serum zinc level in patients with newly diagnosed and resistant alopecia areata Int J Dermatol, 2016
Analysis of serum zinc and copper levels in alopecia areata Ann Dermatol, 1997
Determination of plasma zinc values in patients with alopecia areata Ann Ital Dermatol Sifilogr, 1990
Serum zinc level in alopecia areata patients: a cross-sectional study Dermatol Cosmet, 2012
Zinc aspartate, biotin and clobetasol propionate in the treatment of alopecia areata in childhood J Eur Acad Dermatol Venereol, 1997

Used In Evidence Reviews

A Vitamine D pour Alopecia Areata

D Vitamin A pour Scalp Inflammation (Folliculitis & Dermatitis)

D Vitamin A pour Perte Capillaire par Carence Nutritionnelle

F Zinc pour Alopecia Areata

Combined Diet and Supplementation Therapy Resolves Alopecia Areata in a Paediatric Patient: A Case Study.

Embed This Widget

Study Design

Abstract

Full Text

Figures

Tables

References

Used In Evidence Reviews

Similar Papers

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.

The diagnosis and treatment of iron deficiency and its potential relationship to hair loss.

Comorbidities in alopecia areata: A systematic review and meta-analysis.

Juvenile versus maturity-onset alopecia areata--a comparative retrospective clinical study.

Dermatologic signs in patients with eating disorders.

Vitamin D and the Skin: An Update for Dermatologists.