Meta-analysis of efficacy of platelet-rich plasma therapy for androgenetic alopecia.

A K Gupta, J L Carviel

Meta-Analysis The Journal of dermatological treatment 2017 78 citations

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Study Design

Type d'étude: Meta-Analysis
Taille de l'échantillon: 60
Population: Patients with androgenetic alopecia

Intervention: Meta-analysis of efficacy of platelet-rich plasma therapy for androgenetic alopecia. None
Comparateur: Baseline
Critère de jugement principal: Hair count change
Direction de l'effet: Positive
Risque de biais: Moderate

Abstract

BACKGROUND: Platelet-rich plasma (PRP) therapy is used as an off-label treatment for androgenetic alopecia (AGA); however, published efficacy evidence is still preliminary. OBJECTIVE: Conduct a meta-analysis of current trial data to estimate efficacy. METHODS: Thirteen studies which investigated the use of PRP for treatment of AGA were identified from the literature. A meta-analysis was used to analyze results from four trials (N = 60) where sufficient quantifiable data extraction was possible. All 13 studies were analyzed qualitatively. RESULTS: When comparing PRP treatment to baseline, the overall standardized mean difference was 0.51 [95% confidence interval (CI): 0.14, 0.88; I2 = 0%] in favour of PRP treatment. CONCLUSION: Preliminary results suggest that the investigation of PRP for the treatment of AGA is promising. Controlled trials with quantifiable measures of treatment success are now required to confirm these results.

En bref

Preliminary results suggest that the investigation of PRP for the treatment of AGA is promising, and controlled trials with quantifiable measures of treatment success are now required to confirm these results.

Used In Evidence Reviews

A Thérapie PRP pour Alopécie Androgénétique

Meta-analysis of efficacy of platelet-rich plasma therapy for androgenetic alopecia.

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Study Design

Abstract

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Used In Evidence Reviews

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