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Platelet-rich Plasma as a Potential Treatment for Noncicatricial Alopecias.

Gkini Maria-Angeliki, Kouskoukis Alexandros-Efstratios, Rigopoulos Dimitris, Kouskoukis Konstantinos
Review International journal of trichology 2015 79 citations
PubMed DOI
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Study Design

Type d'étude
Review
Population
alopecia areata patients
Intervention
Platelet-rich Plasma as a Potential Treatment for Noncicatricial Alopecias. None
Comparateur
None
Critère de jugement principal
None
Direction de l'effet
Positive
Risque de biais
Unclear

Abstract

Androgenetic alopecia (AGA) and alopecia areata (AA) are common hair loss disorders affecting both men and women. Despite available therapeutic options, search for new, more effective treatment is constant. Platelet-rich plasma (PRP) could be effective in promoting hair growth: (1) To present PRP and its mechanism of action in promoting hair growth and (2) to evaluate its preparation methods and its therapeutic potential in noncicatrial alopecias in a systematic review. An international bibliography search, through five databases, was conducted to find articles regarding PRP's action on hair loss. Growth factors in platelets' granules of PRP bind in the bulge area of hair follicle, promoting hair growth. In our systematic review, 14 articles matched our criteria, including 12 articles for AGA and two for AA. PRP is a potential useful therapeutic tool for alopecias, without major adverse effects. Nevertheless, due to the small number of conducted trials, further studies are required to investigate its efficacy.

En bref

Platelet-rich plasma (PRP) is a potential useful therapeutic tool for alopecias, without major adverse effects, Nevertheless, due to the small number of conducted trials, further studies are required to investigate its efficacy.

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