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Congenital alopecia areata.

Patsy Lenane, Elena Pope, Bernice Krafchik
Case Report Journal of the American Academy of Dermatology 2005 44 citations
PubMed DOI
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Study Design

Type d'étude
Case Reports
Taille de l'échantillon
4
Population
Neonates/infants with congenital alopecia areata
Durée
156 weeks
Intervention
Congenital alopecia areata. Clobetasol propionate 0.05%, minoxidil 2%
Comparateur
None
Critère de jugement principal
Hair regrowth
Direction de l'effet
Positive
Risque de biais
High

Abstract

Alopecia areata, the alleged autoimmune process leading to nonscarring hair loss, is not uncommon. It has been classified as an acquired cause of alopecia; however, recently it has been reported in the neonatal period. We report 4 cases of congenital alopecia areata with follow-up from 3 to 5 years. The diagnosis was made clinically in all cases. All patients had prolonged periods of quiescence of hair loss ranging from 6 to 24 months. Treatments used included minoxidil 2% and a range of topical steroids including hydrocortisone 1%, betamethasone valerate 0.05%, fluocinonide 0.05%, and clobetasol propionate 0.05%. The best regrowth observed resulted from the use of clobetasol propionate 0.05%, giving full regrowth in 50% of those treated. Alopecia areata can occur at all ages and, thus, can be classified as both an acquired and a congenital disorder resulting in hair loss.

En bref

The diagnosis was made clinically in all cases of congenital alopecia areata with follow-up from 3 to 5 years, and the best regrowth observed resulted from the use of clobetasol propionate, giving full regrowth in 50% of those treated.

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