Description
Experimental findings on adverse effects of 5-alpha-reductase inhibitors in animal models are summarized, providing mechanistic insights into how these drugs may affect the central and peripheral nervous systems.
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Figure 5
Proposed pathophysiological mechanisms underlying the persistent side effects of finasteride are outlined, connecting hormonal disruption to epigenetic changes and altered gut microbiota composition.
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Figure 6
Side effects of treatment with 5-alpha-reductase inhibitors observed in experimental models are comprehensively catalogued, covering reproductive, neurological, and metabolic endpoints.
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Post-finasteride syndrome: An emerging clinical problem.Cite This Figure
 > Source: Silvia Diviccaro et al. "Post-finasteride syndrome: An emerging clinical problem.." *Neurobiology of stress*, 2020. PMID: [32435662](https://pubmed.ncbi.nlm.nih.gov/32435662/)
<figure> <img src="https://pdfs.citedhealth.com/figures/32435662/66.png" alt="Experimental findings on adverse effects of 5-alpha-reductase inhibitors in animal models are summarized, providing mechanistic insights into how these drugs may affect the central and peripheral nervous systems." /> <figcaption>Figure 4. Experimental findings on adverse effects of 5-alpha-reductase inhibitors in animal models are summarized, providing mechanistic insights into how these drugs may affect the central and peripheral nervous systems.<br> Source: Silvia Diviccaro et al. "Post-finasteride syndrome: An emerging clinical problem.." <em>Neurobiology of stress</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32435662/">32435662</a></figcaption> </figure>