Platelet-rich Plasma as a Potential Treatment for Noncicatricial Alopecias.

Gkini Maria-Angeliki, Kouskoukis Alexandros-Efstratios, Rigopoulos Dimitris, Kouskoukis Konstantinos

Review International journal of trichology 2015 79 citas

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Study Design

Tipo de estudio: Review
Población: alopecia areata patients

Intervención: Platelet-rich Plasma as a Potential Treatment for Noncicatricial Alopecias. None
Comparador: None
Resultado primario: None
Dirección del efecto: Positive
Riesgo de sesgo: Unclear

Abstract

Androgenetic alopecia (AGA) and alopecia areata (AA) are common hair loss disorders affecting both men and women. Despite available therapeutic options, search for new, more effective treatment is constant. Platelet-rich plasma (PRP) could be effective in promoting hair growth: (1) To present PRP and its mechanism of action in promoting hair growth and (2) to evaluate its preparation methods and its therapeutic potential in noncicatrial alopecias in a systematic review. An international bibliography search, through five databases, was conducted to find articles regarding PRP's action on hair loss. Growth factors in platelets' granules of PRP bind in the bulge area of hair follicle, promoting hair growth. In our systematic review, 14 articles matched our criteria, including 12 articles for AGA and two for AA. PRP is a potential useful therapeutic tool for alopecias, without major adverse effects. Nevertheless, due to the small number of conducted trials, further studies are required to investigate its efficacy.

TL;DR

Platelet-rich plasma (PRP) is a potential useful therapeutic tool for alopecias, without major adverse effects, Nevertheless, due to the small number of conducted trials, further studies are required to investigate its efficacy.

Used In Evidence Reviews

A Terapia PRP para Alopecia Areata

A Terapia PRP para Alopecia Androgenética

Platelet-rich Plasma as a Potential Treatment for Noncicatricial Alopecias.

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Study Design

Abstract

TL;DR

Used In Evidence Reviews

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