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Congenital alopecia areata.

Patsy Lenane, Elena Pope, Bernice Krafchik
Case Report Journal of the American Academy of Dermatology 2005 44 Zitierungen
PubMed DOI
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Study Design

Studientyp
Case Reports
Stichprobengröße
4
Population
Neonates/infants with congenital alopecia areata
Dauer
156 weeks
Intervention
Congenital alopecia areata. Clobetasol propionate 0.05%, minoxidil 2%
Vergleichsgruppe
None
Primärer Endpunkt
Hair regrowth
Wirkungsrichtung
Positive
Verzerrungsrisiko
High

Abstract

Alopecia areata, the alleged autoimmune process leading to nonscarring hair loss, is not uncommon. It has been classified as an acquired cause of alopecia; however, recently it has been reported in the neonatal period. We report 4 cases of congenital alopecia areata with follow-up from 3 to 5 years. The diagnosis was made clinically in all cases. All patients had prolonged periods of quiescence of hair loss ranging from 6 to 24 months. Treatments used included minoxidil 2% and a range of topical steroids including hydrocortisone 1%, betamethasone valerate 0.05%, fluocinonide 0.05%, and clobetasol propionate 0.05%. The best regrowth observed resulted from the use of clobetasol propionate 0.05%, giving full regrowth in 50% of those treated. Alopecia areata can occur at all ages and, thus, can be classified as both an acquired and a congenital disorder resulting in hair loss.

Zusammenfassung

The diagnosis was made clinically in all cases of congenital alopecia areata with follow-up from 3 to 5 years, and the best regrowth observed resulted from the use of clobetasol propionate, giving full regrowth in 50% of those treated.

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