Meta-analysis of efficacy of platelet-rich plasma therapy for androgenetic alopecia.
Study Design
- نوع الدراسة
- Meta-Analysis
- حجم العينة
- 60
- المجتمع المدروس
- Patients with androgenetic alopecia
- التدخل
- Meta-analysis of efficacy of platelet-rich plasma therapy for androgenetic alopecia. None
- المقارن
- Baseline
- النتيجة الأولية
- Hair count change
- اتجاه التأثير
- Positive
- خطر التحيز
- Moderate
Abstract
BACKGROUND: Platelet-rich plasma (PRP) therapy is used as an off-label treatment for androgenetic alopecia (AGA); however, published efficacy evidence is still preliminary. OBJECTIVE: Conduct a meta-analysis of current trial data to estimate efficacy. METHODS: Thirteen studies which investigated the use of PRP for treatment of AGA were identified from the literature. A meta-analysis was used to analyze results from four trials (N = 60) where sufficient quantifiable data extraction was possible. All 13 studies were analyzed qualitatively. RESULTS: When comparing PRP treatment to baseline, the overall standardized mean difference was 0.51 [95% confidence interval (CI): 0.14, 0.88; I2 = 0%] in favour of PRP treatment. CONCLUSION: Preliminary results suggest that the investigation of PRP for the treatment of AGA is promising. Controlled trials with quantifiable measures of treatment success are now required to confirm these results.
باختصار
Preliminary results suggest that the investigation of PRP for the treatment of AGA is promising, and controlled trials with quantifiable measures of treatment success are now required to confirm these results.
Used In Evidence Reviews
Similar Papers
Journal of cosmetic dermatology · 2021
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
Stem cells translational medicine · 2015
The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial.
Clinical reviews in allergy & immunology · 2021
Alopecia Areata: an Update on Etiopathogenesis, Diagnosis, and Management.
Cells · 2019
Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development.
The British journal of dermatology · 2013
A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata.
Journal of the European Academy of Dermatology and Venereology : JEADV · 2018